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Studies with antibodies that recognize total APAP protein adducts showed that adducts were specific biomarkers of APAP toxicity (Potter et al

J Neurosci 40(9):19751986 Rieck M et al (2015) Is there a role for ADORA2A polymorphisms in levodopa-induced dyskinesia in Parkinsons disease patients

To conceptualize the shared and distinct mechanisms of glial autophagic failure across these diverse pathologies, Table 1 provides a comparative synthesis of the primary protein aggregates, specific autophagic defects, and the resulting glial and neuronal consequences in AD, PD, HD, and ALS